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        <title><![CDATA[ Health & Pharma ]]></title>
        <link><![CDATA[ https://healthandpharma.net//feed ]]></link>
        <description><![CDATA[ Health and Pharma is a new-generation international news and communication platform. We strive to be a top-tier trusted news outlet, delivering firsthand reports from reliable channels. Our goal is to collaborate with health science and pharma professionals. ]]></description>
        <language>en</language>
        <pubDate>Sat, 09 May 2026 22:52:09 UTC</pubDate>
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                    <item>
                <title><![CDATA[FDA Grants RMAT Designation to RZ-001, a Novel RNA Therapy for Hepatocellular Carcinoma]]></title>
                <link>https://healthandpharma.net/fda-rmat-rz001-rna-therapy-hepatocellular-carcinoma-rznomics</link>
                <description><![CDATA[The FDA has granted RMAT designation to RZ-001, Rznomics’ investigational trans-splicing ribozyme-based RNA therapy for hepatocellular carcinoma. The designation is supported by promising Phase 1b/2a safety and preliminary response data presented at AACR 2026.]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1158 at Health&Pharma]]></guid>
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                <pubDate>Sat, 09 May 2026 21:34:21 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA Approves Bizengri as First Targeted Therapy for NRG1 Fusion+ Cholangiocarcinoma]]></title>
                <link>https://healthandpharma.net/fda-approves-bizengri-zenocutuzumab-cholangiocarcinoma</link>
                <description><![CDATA[The FDA has approved zenocutuzumab-zbco (BIZENGRI) for adults with advanced, unresectable or metastatic NRG1 fusion-positive cholangiocarcinoma after prior systemic therapy. In the Phase 2 eNRGy trial, the confirmed ORR was 36.8%]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1157 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1778352696fda-Bizengri-Zenocutuzumab.webp"/>
                <pubDate>Sat, 09 May 2026 18:51:36 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA Grants Fast Track Designation to RPTR-1-201 for Advanced Triple- Breast Cancer]]></title>
                <link>https://healthandpharma.net/fda-fast-track-designation-rptr1-201-triple-breast-cancer</link>
                <description><![CDATA[The FDA has granted Fast Track Designation to RPTR-1-201 for unresectable or metastatic triple-negative breast cancer after standard therapy failure or intolerance. The investigational TCR bispecific, now in Phase 1/2 testing, uses an engineered TCR and anti-CD3 domain]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1156 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1778245593FDA-RPTR1-201.webp"/>
                <pubDate>Fri, 08 May 2026 13:06:33 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[PHERGain Data Support Chemo-Free Treatment With 90% Five-Year RFS in Breast Cancer]]></title>
                <link>https://healthandpharma.net/esmo-breast26-phergain-chemotherapy-free-survival-breast-cancer</link>
                <description><![CDATA[New PHERGain data presented at #ESMObreast26 strengthen the rationale for chemotherapy de-escalation in selected patients with early HER2+ breast cancer. And about one-third of patients avoided chemotherapy, with nearly 90% remaining relapse-free five years after surgery.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[admin@healthandmedicine.net (Hüseyin Kandemir)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1155 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1778174820PHERGain-ESMO-BC-2026.webp"/>
                <pubDate>Thu, 07 May 2026 17:04:59 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA Grants Fast Track Designation to Dubodencel for Advanced Cutaneous Melanoma]]></title>
                <link>https://healthandpharma.net/fda-designation-dubodencel-doc1021-cutaneous-melanoma</link>
                <description><![CDATA[The FDA has granted Fast Track designation to dubodencel (DOC1021) for unresectable or metastatic cutaneous melanoma. The first-in-class, patient-derived, double-loaded dendritic cell therapy uses tumor lysate and amplified tumor-derived mRNA to stimulate broad anti-tumor immunity.]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1154 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1778115136FDA-Dubodencel-2.webp"/>
                <pubDate>Thu, 07 May 2026 00:52:16 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Targeting RNase H2 Exposes a New Therapeutic Vulnerability in Triple-Negative Breast Cancer]]></title>
                <link>https://healthandpharma.net/rnase-h2-exposes-triple-breast-cancer</link>
                <description><![CDATA[Researchers at MD Anderson have identified RNase H2 as a key survival mechanism in triple-negative breast cancer, helping tumor cells tolerate high levels of DNA replication stress.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[admin@healthandmedicine.net (Hüseyin Kandemir)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1153 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1778110298RNase-H2-Breast-Cancer-1.webp"/>
                <pubDate>Wed, 06 May 2026 23:26:46 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA Accepts IBTROZI sNDA After Durable Long-Term Benefit in Advanced ROS1+ Lung Cancer]]></title>
                <link>https://healthandpharma.net/fda-taletrectinib-ibtrozi-snda-ros1-lung-cancer</link>
                <description><![CDATA[The FDA has accepted the sNDA for IBTROZI® (taletrectinib), which aims to update the drug’s label with longer-term data in advanced ROS1-positive non-small cell lung cancer. In TRUST-I, TKI-naïve patients achieved a median duration of response of 49.7 months]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1152 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1778105422IBTROZI-taletrectinib-fda-1.webp"/>
                <pubDate>Wed, 06 May 2026 22:10:22 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[ALK Mutation Emerges as a Potential Biomarker for Pan-Cancer Immunotherapy Benefit]]></title>
                <link>https://healthandpharma.net/cancer-alk-mutation-immunotherapy-checkpoint-inhibitors</link>
                <description><![CDATA[A pan-cancer analysis of 2,930 patients across 11 tumor types found that ALK mutation was associated with significantly improved survival among patients treated with immune checkpoint inhibitors. Patients with ALK-mutant tumors had a 31% lower risk of death,]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[admin@healthandmedicine.net (Hüseyin Kandemir)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1151 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777937349alk-immunotherapy-tumor-2.webp"/>
                <pubDate>Mon, 04 May 2026 23:27:41 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA ODAC Backs Truqap Combination for PTEN-Deficient Metastatic Prostate Cancer]]></title>
                <link>https://healthandpharma.net/fda-truqap-prostate-cancer-capivasertib</link>
                <description><![CDATA[FDA’s advisory committee has endorsed Truqap plus abiraterone and ADT as a treatment option with a favorable benefit-risk profile for patients with PTEN-deficient metastatic HS prostate cancer. In CAPItello-281, the combination reduced radiographic progression or death by 19%]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1150 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777847245Truqap-capivasertib-FDA-1.webp"/>
                <pubDate>Sun, 03 May 2026 22:27:25 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Zeta Navigation System Gains FDA Clearance for Brain Tumor Biopsy and Neurosurgery]]></title>
                <link>https://healthandpharma.net/fda-ai-zeta-navigation-system-brain-tumor-biopsy-surgery</link>
                <description><![CDATA[The Zeta Navigation System has received FDA 510(k) clearance alongside the Zeta Stylet and Zeta Bolt, expanding real-time, AI-assisted image guidance for neurosurgery. The platform may improve access to millimeter-level navigation for brain tumor biopsies]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1149 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777831156zeta-brain-surgery.webp"/>
                <pubDate>Sun, 03 May 2026 17:59:16 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA Approves Vepdegestrant, First PROTAC Therapy for ESR1+ ER+/HER2- Breast Cancer]]></title>
                <link>https://healthandpharma.net/fda-vepdegestrant-veppanu-breast-cancer</link>
                <description><![CDATA[FDA has approved vepdegestrant (VEPPANU), the first PROTAC therapy, for adults with ESR1-mutated ER+/HER2- advanced or metastatic breast cancer after endocrine therapy progression. In VERITAC-2, vepdegestrant reduced risk of progression or death by 43%]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1148 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777760226Vepdegestrant-Veppanu-fda.webp"/>
                <pubDate>Sat, 02 May 2026 22:17:06 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Misinformation Drives Over 16 Million Americans Toward High Skin Cancer Risk]]></title>
                <link>https://healthandpharma.net/social-media-misinformation-skin-cancer-risk-sunscreen</link>
                <description><![CDATA[A new American Academy of Dermatology survey finds that social media misinformation has driven more than 16 million U.S. adults toward higher skin cancer risk by leading them to reduce or stop using sunscreen.]]></description>
                <category>Clinical Trials</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1147 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777729500skin-cancer-sunscreen-2.webp"/>
                <pubDate>Sat, 02 May 2026 13:45:00 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[SUNRISE-II Trial Begins Evaluating Ultrasound-Guided HIFU Ablation for Pancreatic Cancer]]></title>
                <link>https://healthandpharma.net/suizenji-hifu-ablation-pancreatic-cancer</link>
                <description><![CDATA[Sonire’s first U.S. study of ultrasound-guided, anesthesia-free HIFU ablation therapy has been launched for patients with unresectable pancreatic cancer. The Stanford-led, open-label trial will enroll patients to assess safety, and tolerability before first-line chemotherapy.]]></description>
                <category>Clinical Trials</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1146 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777670234Suizenji-HIFU-Ablation-2.webp"/>
                <pubDate>Fri, 01 May 2026 21:17:14 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Restoring Proteostasis May Boost T Cell Function and Open a New Route for Immunotherapy]]></title>
                <link>https://healthandpharma.net/restoring-proteostasis-boost-tcell-cancer-immunotherapy</link>
                <description><![CDATA[A new Cell study suggests that T cell exhaustion in tumors is driven in part by failed proteostasis, causing damaged and misfolded proteins to accumulate inside tumor-infiltrating lymphocytes. Restoring proteostasis may improved T cell function]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[admin@healthandmedicine.net (Hüseyin Kandemir)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1145 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777584232proteostasis-tcell-cancer-immunotherapy-1.webp"/>
                <pubDate>Thu, 30 Apr 2026 21:23:52 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[OPTIMAL Data Support TLX597-Tx as a Next-Gen Radioligand Therapy in Prostate Cancer]]></title>
                <link>https://healthandpharma.net/tlx597tx-radioligand-therapy-prostate-cancer-telix</link>
                <description><![CDATA[Phase 2 OPTIMAL-PSMA dosimetry data suggest that TLX597-Tx, a next-generation PSMA-targeting radioligand therapy, demonstrated low salivary gland and kidney uptake in metastatic castration-resistant prostate cancer.]]></description>
                <category>Clinical Trials</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1144 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777504718TLX597Tx-PSMA-Radioligand-Prostate-Cancer.webp"/>
                <pubDate>Wed, 29 Apr 2026 23:18:38 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[AidaBREAST Gains FDA Breakthrough Status for Personalized Radiotherapy in Breast Cancer]]></title>
                <link>https://healthandpharma.net/aidabreast-test-fda-radiotherapy-breast-cancer</link>
                <description><![CDATA[AidaBREAST® received FDA Breakthrough Device designation as a multi-omic assay for women with stage I–IIa invasive breast cancer. The test estimates 10-year locoregional recurrence risk and predicts benefit from radiation therapy after breast surgery]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1143 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1765908521Lab-test-bio-cancer-43.webp"/>
                <pubDate>Wed, 29 Apr 2026 16:34:46 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Phase 3 MagnetisMM-5 Trial Supports Earlier Use of Elranatamab in Relapsed Myeloma]]></title>
                <link>https://healthandpharma.net/elranatamab-elrexfio-multiple-myelom-pfizer</link>
                <description><![CDATA[The Phase 3 MagnetisMM-5 trial showed that elranatamab (ELREXFIO) significantly improved progression-free survival versus daratumumab plus pomalidomide and dexamethasone in adults with relapsed or refractory multiple myeloma.]]></description>
                <category>Clinical Trials</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1142 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777471846Adc-cell-Myeloma-2.webp"/>
                <pubDate>Wed, 29 Apr 2026 14:07:00 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Real-World Analysis Links Community Oncology Care to Longer Survival in Multi-Cancer]]></title>
                <link>https://healthandpharma.net/community-oncology-care-survival-breast-lung-cancer</link>
                <description><![CDATA[A real-world Flatiron Health analysis commissioned by the Community Oncology Alliance found that patients with de novo metastatic breast cancer and lung cancer treated in independent community oncology practices had survival outcomes exceeding SEER benchmarks.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[admin@healthandmedicine.net (Hüseyin Kandemir)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1141 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777387052cancer-patient-oncology-2.webp"/>
                <pubDate>Tue, 28 Apr 2026 14:24:07 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Early CAR T-Cell Intervention Shows Disease-Eradication Potential in High-Risk Myeloma]]></title>
                <link>https://healthandpharma.net/cart-cell-ciltacabtagene-smoldering-multiple-myeloma</link>
                <description><![CDATA[A Dana-Farber phase 2 trial suggests BCMA-directed CAR T-cell therapy may deliver deep early disease control in high-risk smoldering multiple myeloma. All 20 patients receiving cilta-cel achieved MRD negativity within two months and remained MRD-negative after 15.3 months]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[admin@healthandmedicine.net (Hüseyin Kandemir)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1140 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777471620Adc-cell-Myeloma-1.webp"/>
                <pubDate>Mon, 27 Apr 2026 16:31:37 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Dual Pathway Blockade Achieves 40% Response in Clear Cell Gynaecological Cancer]]></title>
                <link>https://healthandpharma.net/pembrolizumab-lenvatinib-clear-cell-gynaecological-cancer</link>
                <description><![CDATA[The Phase 2 LARA trial reported encouraging activity for pembrolizumab plus lenvatinib in recurrent gynaecological clear cell carcinoma, achieving a 40% objective response rate within 24 weeks and a median progression-free survival of 6.4 months.]]></description>
                <category>Clinical Trials</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1139 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1758406106cancer-cell-focus.webp"/>
                <pubDate>Mon, 27 Apr 2026 14:36:39 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[World’s First Nectin-4-Targeting ADC Enters Phase III Trial in Triple-Negative Breast Cancer]]></title>
                <link>https://healthandpharma.net/nectin4-adc-breast-cancer-9mw2821-tnbc-mabwell</link>
                <description><![CDATA[The world’s first Nectin-4-targeting ADC to enter Phase III development in triple-negative breast cancer is now being evaluated in locally advanced or metastatic disease. The randomized trial will compare 9MW2821 with investigator’s choice of chemotherapy in patients]]></description>
                <category>Clinical Trials</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1138 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777133693ADC-Mabwell-Nectin-4.webp"/>
                <pubDate>Sat, 25 Apr 2026 16:14:53 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Long-Term Data Show Taletrectinib Delivers High Response Rates in ROS1+ NSCLC]]></title>
                <link>https://healthandpharma.net/ibtrozi-taletrectinib-nsclc-lung-cancer</link>
                <description><![CDATA[Long-term pooled results from TRUST-I /-II trials show taletrectinib delivers durable benefit in advanced ROS1+ NSCLC, with an 89.8% response rate, 49.7-month median duration of response, and 46.1-month median progression-free survival in TKI-naïve patients.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1137 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776980082Ibtrozi-taletrectinib-cancer.webp"/>
                <pubDate>Thu, 23 Apr 2026 21:34:42 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA-Cleared Utepreva Device Aims to Improve Early Endometrial Cancer Detection]]></title>
                <link>https://healthandpharma.net/fda-utepreva-device-endometrial-cancer-detection-test</link>
                <description><![CDATA[The FDA 510(k)-cleared Utepreva Endometrial Sampler, a single-use device designed to support early diagnostic evaluation of endometrial cancer, may help improve diagnostic assessment.]]></description>
                <category>Cancer</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1136 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776965964Utepreva-cancer-test.webp"/>
                <pubDate>Thu, 23 Apr 2026 17:39:24 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[PLN-101095 Plus Pembrolizumab Shows Durable Responses in ICI-R Solid Tumors]]></title>
                <link>https://healthandpharma.net/pln-101095-checkpoint-inhibitor-pembrolizumab-solid-tumors</link>
                <description><![CDATA[Updated Phase 1 data presented at AACR 2026 suggest PLN-101095 plus pembrolizumab may help overcome secondary ICI resistance in advanced solid tumors. Among confirmed responders, average maximum tumor reduction reached 89% and median treatment duration was 19 months.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1135 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1777587462Checkpoint-inhibitor-Tumors-32.webp"/>
                <pubDate>Wed, 22 Apr 2026 23:49:46 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Opaganib Shows Dual Preclinical Promise in Neuroblastoma and Triple- Breast Cancer]]></title>
                <link>https://healthandpharma.net/opaganib-neuroblastoma-breast-cancer</link>
                <description><![CDATA[New preclinical data presented at AACR 2026 suggest opaganib may improve outcomes in two hard-to-treat cancers. In high-risk neuroblastoma models, it enhanced oxaliplatin plus doxorubicin activity by destabilizing n-Myc and promoting apoptosis.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1134 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776895528Opaganib-Breast-Cancer.webp"/>
                <pubDate>Wed, 22 Apr 2026 22:05:28 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Ozekibart Shows Encouraging Late-Line Activity in Metastatic Colorectal Cancer]]></title>
                <link>https://healthandpharma.net/ozekibart-folfiri-metastatic-colorectal-cancer</link>
                <description><![CDATA[Updated Phase 1/2 data show that ozekibart plus FOLFIRI produced a 20% objective response rate and an 87% disease control rate in heavily pretreated metastatic or unresectable colorectal cancer, where historical response rates are typically 1% to 6%.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1133 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776875903Ozekibart-Colorectal-Cancer.webp"/>
                <pubDate>Wed, 22 Apr 2026 16:38:24 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA Grants Breakthrough Status to First Viral Liquid Biopsy in Hepatocellular Carcinoma]]></title>
                <link>https://healthandpharma.net/fda-breakthrough-viral-mrd-liquid-biopsy-hepatocellular-carcinoma</link>
                <description><![CDATA[The FDA has granted Breakthrough Device Designation to CatCHimera, the first MRD liquid biopsy in hepatocellular carcinoma to track HBV-host integration junctions rather than somatic mutations. In clinical studies, it detected viral-host DNA in 98% of pre-surgical plasma samples,]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1132 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776859908FDA-TCM-Biotech-CatCHimera.webp"/>
                <pubDate>Wed, 22 Apr 2026 12:11:48 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA Gives Priority Review to PADCEV Plus Pembrolizumab in MI Bladder Cancer]]></title>
                <link>https://healthandpharma.net/fda-priority-padcev-pembrolizumab-mi-bladder-cancer</link>
                <description><![CDATA[The FDA has granted Priority Review to a supplemental application for PADCEV plus pembrolizumab in muscle-invasive bladder cancer, regardless of cisplatin eligibility. In the Phase 3 EV-304 trial, the regimen reduced the risk of recurrence, progression, or death by 47%]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1131 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776728888PADCEV-Pembrolizumab-13.webp"/>
                <pubDate>Mon, 20 Apr 2026 23:48:08 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[AACR26 Data Show Multi-Biomarker MCED Approach Improves Early Cancer Detection]]></title>
                <link>https://healthandpharma.net/aacr2026-abbott-biomarker-mced-cancer-detection</link>
                <description><![CDATA[At AACR 2026, Abbott presented data on Cancerguard, a multi-biomarker blood-based MCED test that combines methylation and protein signals to improve cancer detection. In 3,163 samples, 47.1% of positive calls were methylation-only, 7.4% protein-only, and 45.5% dual-signal.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1130 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776525575Abbott-cancer-guard.webp"/>
                <pubDate>Sat, 18 Apr 2026 15:19:35 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA Grants Breakthrough Status to First Urine-Based Multi-Cancer Early Detection Test]]></title>
                <link>https://healthandpharma.net/fda-breakthrough-urine-cancer-detection-test-toby</link>
                <description><![CDATA[TOBY’s urine-based MCED test received FDA Breakthrough Device Designation. This is the first urine-based MCED platform granted this status. The test analyzes urinary VOCs using spectroscopy and machine learning from a single sample.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1129 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776459479Urine-mced-cancer-test.webp"/>
                <pubDate>Fri, 17 Apr 2026 20:57:59 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Daraxonrasib Doubles Overall Survival in Previously Treated Metastatic Pancreatic Cancer]]></title>
                <link>https://healthandpharma.net/daraxonrasib-metastatic-pancreatic-cancer</link>
                <description><![CDATA[Daraxonrasib significantly improved outcomes in the Phase 3 RASolute 302 trial in previously treated metastatic pancreatic cancer, meeting all primary and key secondary endpoints. In the intent-to-treat population, median overall survival was 13.2 months versus 6.7 months with chemotherapy.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1128 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776297655Pancreatic-Cancer-1.webp"/>
                <pubDate>Thu, 16 Apr 2026 00:00:55 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[AI Nodule Detection Helps Sarasota Memorial Reach 75% Early Lung Cancer Diagnosis]]></title>
                <link>https://healthandpharma.net/ai-nodule-detection-sarasota-memorial-lung-cancer</link>
                <description><![CDATA[Sarasota Memorial reported that 75% of lung cancers diagnosed through its early detection program were found at Stage I or II. The program used AI to review more than 430,000 radiology reports annually and flag incidental pulmonary nodules.]]></description>
                <category>AI</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1127 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776287154Sarasota Memoria.webp"/>
                <pubDate>Wed, 15 Apr 2026 21:05:54 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Illumina Launch 100 K Genome Effort to Advance Cancer and Rare Disease Research]]></title>
                <link>https://healthandpharma.net/illumina-d3b-genome-pediatric-cancer-rare-disease</link>
                <description><![CDATA[Illumina and D3b, have announced a new data partnership aimed at accelerating research in pediatric cancer and rare disease, two areas where fragmented data and delayed diagnosis continue to limit progress.]]></description>
                <category>AI</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1126 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1722871025asco-illumina-23.webp"/>
                <pubDate>Wed, 15 Apr 2026 14:59:41 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Zenocutuzumab Gains NCCN Support as FDA Review Advances in Cholangiocarcinoma]]></title>
                <link>https://healthandpharma.net/bizengri-zenocutuzumab-fda-bla-cholangiocarcinoma</link>
                <description><![CDATA[Partner Therapeutics has submitted a supplemental Biologics License Application to the U.S. FDA for BIZENGRI, zenocutuzumab-zbco, seeking approval in adults with advanced unresectable or metastatic cholangiocarcinoma harboring an NRG1 gene fusion.]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1125 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776261381BIZENGRI-zenocutuzumab-12.webp"/>
                <pubDate>Wed, 15 Apr 2026 13:56:21 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Phase 2 Data Position Trastuzumab Pamirtecan as a Promising Option in Endometrial Cancer]]></title>
                <link>https://healthandpharma.net/biontech-trastuzumab-pamirtecan-her2-endometrial-cancer</link>
                <description><![CDATA[BioNTech and DualityBio reported encouraging Phase 2 results for trastuzumab pamirtecan, an investigational HER2-targeted antibody-drug conjugate, in pretreated, HER2-expressing recurrent endometrial cancer.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1124 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776173656BioNTech-Trastuzumab-Pamirtecan-2.webp"/>
                <pubDate>Tue, 14 Apr 2026 13:34:16 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Mocertatug Rezetecan Shows Strong Responses in Ovarian and Endometrial Cancers]]></title>
                <link>https://healthandpharma.net/gsk-mocertatug-rezetecan-ovarian-endometrial-cancers</link>
                <description><![CDATA[GSK has reported encouraging early clinical data from the global phase I BEHOLD-1 trial of mocertatug rezetecan, a B7-H4-targeted antibody-drug conjugate, in patients with platinum-resistant ovarian cancer and recurrent or advanced endometrial cancer,]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1123 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776112371GSK-Mocertatug-Rezetecan.webp"/>
                <pubDate>Mon, 13 Apr 2026 20:32:51 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[FDA Grants Priority Review to Ifinatamab Deruxtecan in Pretreated ES-SC Lung Cancer]]></title>
                <link>https://healthandpharma.net/fda-ifinatamab-deruxtecan-essc-lung-cancer</link>
                <description><![CDATA[FDA has accepted and granted Priority Review to the biologics license application for ifinatamab deruxtecan in adults with extensive-stage small cell lung cancer, ES-SCLC, whose disease progressed on or after platinum-based chemotherapy.]]></description>
                <category>FDA &amp; EMA</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1122 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776106086Ifinatamab-Deruxte-lung-cancer-1.webp"/>
                <pubDate>Mon, 13 Apr 2026 18:48:06 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[MD Anderson Study Identifies DPY30 as Therapeutic Target in Pancreatic Cancer]]></title>
                <link>https://healthandpharma.net/md-anderson-dyp30-biomarker-target-pancreatic-cancer</link>
                <description><![CDATA[Researchers at MD Anderson identified DPY30 as a key biomarker and epigenetic regulator that enables pancreatic tumors to tolerate replication stress and escape immune attack. Loss of DPY30 destabilized replication forks, increased T-cell infiltration]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1121 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1776096868DPY30-Pancreatic-Cancer-4.webp"/>
                <pubDate>Mon, 13 Apr 2026 16:14:28 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[Blocking DHODH Helps Triple Combination Overcome Resistance in Lung Cancer]]></title>
                <link>https://healthandpharma.net/dhodh-radiotherapy-lung-cancer-ferroptosis-leflunomide</link>
                <description><![CDATA[Researchers from MD Anderson identified DHODH as a key metabolic driver of radiotherapy resistance in lung cancer. Radiation increased DHODH activity, enabling tumor cells to suppress ferroptosis and support DNA repair.]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[info@healthandpharma.net (Health and Pharma)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1120 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/pharma-drug-radioligand-41.webp"/>
                <pubDate>Sat, 11 Apr 2026 21:55:16 UTC</pubDate>
            </item>
                    <item>
                <title><![CDATA[New Strategy Blocks NMD, Unmasks Hidden Tumor Antigens, and Boosts Immunotherapy]]></title>
                <link>https://healthandpharma.net/blocks-nmd-hidden-tumor-immunotherapy-cancer</link>
                <description><![CDATA[A new study led by UCL researchers suggests that making cancer cells more visible to the immune system could broaden the impact of immunotherapy across multiple tumor types. Published in Immunity and based on data from more than 1,000 patients]]></description>
                <category>ONCOLife</category>
                <author><![CDATA[admin@healthandmedicine.net (Hüseyin Kandemir)]]></author>
                <guid isPermaLink="false"><![CDATA[article 1119 at Health&Pharma]]></guid>
                <media:content width="140" url="https://healthandpharma.net/images/test/1755462288Cancer-stem-cells-2.webp"/>
                <pubDate>Sat, 11 Apr 2026 16:43:09 UTC</pubDate>
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